Name
As of 06/01/2026Price
Aum/Mkt Cap
YIELD
Exp Ratio
Watchlist
Vitals
YTD Return
2.1%
1 yr return
36.2%
3 Yr Avg Return
6.9%
5 Yr Avg Return
4.8%
Net Assets
$39.4 M
Holdings in Top 10
46.8%
52 WEEK LOW AND HIGH
Expenses
OPERATING FEES
Expense Ratio 2.88%
SALES FEES
Front Load N/A
Deferred Load N/A
TRADING FEES
Turnover N/A
Redemption Fee N/A
Min Investment
Standard (Taxable)
$2,500
IRA
$2,500
Fund Classification
Fund Type
Open End Mutual Fund
Name
As of 06/01/2026Price
Aum/Mkt Cap
YIELD
Exp Ratio
Watchlist
LYFCX - Profile
Distributions
- YTD Total Return 2.1%
- 3 Yr Annualized Total Return 6.9%
- 5 Yr Annualized Total Return 4.8%
- Capital Gain Distribution Frequency N/A
- Net Income Ratio -2.21%
- Dividend Yield 0.7%
- Dividend Distribution Frequency Annual
Fund Details
-
Legal NameAlphaCentric Life Sciences and Healthcare Fund
-
Fund Family NameMutual Fund Series Trust
-
Inception DateNov 29, 2019
-
Shares OutstandingN/A
-
Share ClassC
-
CurrencyUSD
-
Domiciled CountryUS
-
ManagerMark Charest
Fund Description
The Fund seeks to achieve its investment objective by investing in the life sciences and healthcare related companies that the Funds investment sub-advisor, Kennedy Capital Management LLC (the Sub-Advisor), believes have the potential to appreciate in value. Under normal market conditions, the Fund invests at least 80% of its net assets plus borrowings for investment purposes in the securities of companies in the life sciences and healthcare sectors, which the Fund defines to be the category of companies related to producing or supplying facilities, supplies, technology, pharmaceuticals, equipment, devices or services for the preservation and care of a persons or animals health. The Fund invests in equity securities, primarily common stock, of these companies and may also invest, from time to time, in exchange traded funds (ETFs) that primarily invest in these companies. The Fund defines life sciences and healthcare companies to include those companies that are expected to derive 50% or more of their revenue from life sciences and healthcare related products and services. These companies may include development stage companies, which are entities devoting substantially all of their efforts to establishing a business for which commercial operations have not commenced or no significant revenue is being generated.
The Fund may invest up to 15% of the Funds net assets in private and other companies whose securities may have legal or contractual restrictions on resale or are otherwise illiquid such as initial public offerings (IPOs), mezzanine financing offerings and other structured transactions. The Fund may invest in securities of companies of any market capitalization and in foreign companies, either directly or through American Depositary Receipts (ADRs).
The Fund concentrates its investments (i.e., invests more than 25% of its assets) in the biotech and pharmaceutical; health care facilities and services; and medical equipment and devices industries, collectively. Each of these industries are commonly categorized within the healthcare sector because they share similar distribution channels and regulatory constraints.
For hedging purposes, or when the Sub-Advisor anticipates significant price changes due to company or market moving events, the Fund may also invest in inverse ETFs and purchase and sell call and put options on equity securities of life sciences and healthcare companies.
The Sub-Advisor begins the investment selection process by systematically screening the universe of life sciences and healthcare companies using fundamental scientific and medical literature review, and input from leading scientific and medical experts, to identify highly innovative thematic areas of interest. Financial analysis, market projections and corporate diligence are then performed to select the Funds investments.
The Fund actively trades its portfolio investments, which may lead to higher transaction costs that may affect the Funds performance.
LYFCX - Performance
Return Ranking - Trailing
| Period | LYFCX Return | Category Return Low | Category Return High | Rank in Category (%) |
|---|---|---|---|---|
| YTD | 2.1% | -22.9% | 20.0% | 26.88% |
| 1 Yr | 36.2% | -20.4% | 134.5% | 25.00% |
| 3 Yr | 6.9%* | -6.3% | 23.9% | 43.75% |
| 5 Yr | 4.8%* | -15.5% | 12.3% | 34.19% |
| 10 Yr | N/A* | 3.0% | 13.1% | N/A |
* Annualized
Return Ranking - Calendar
| Period | LYFCX Return | Category Return Low | Category Return High | Rank in Category (%) |
|---|---|---|---|---|
| 2025 | 26.0% | -21.9% | 61.0% | 15.00% |
| 2024 | -2.3% | -28.2% | 19.2% | 51.88% |
| 2023 | 3.3% | -8.6% | 19.0% | 43.75% |
| 2022 | -6.2% | -53.9% | 3.2% | 14.19% |
| 2021 | -15.0% | -39.6% | 24.2% | 79.35% |
Total Return Ranking - Trailing
| Period | LYFCX Return | Category Return Low | Category Return High | Rank in Category (%) |
|---|---|---|---|---|
| YTD | 2.1% | -22.9% | 20.0% | 26.88% |
| 1 Yr | 36.2% | -20.4% | 134.5% | 25.00% |
| 3 Yr | 6.9%* | -6.3% | 23.9% | 43.75% |
| 5 Yr | 4.8%* | -15.5% | 12.3% | 34.19% |
| 10 Yr | N/A* | 3.0% | 13.1% | N/A |
* Annualized
Total Return Ranking - Calendar
| Period | LYFCX Return | Category Return Low | Category Return High | Rank in Category (%) |
|---|---|---|---|---|
| 2025 | 26.9% | -0.5% | 63.7% | 21.88% |
| 2024 | -1.2% | -28.2% | 19.2% | 88.75% |
| 2023 | 6.1% | -8.6% | 19.0% | 30.63% |
| 2022 | -1.8% | -53.9% | 3.7% | 10.32% |
| 2021 | -4.3% | -33.9% | 26.0% | 89.68% |
NAV & Total Return History
LYFCX - Holdings
Concentration Analysis
| LYFCX | Category Low | Category High | LYFCX % Rank | |
|---|---|---|---|---|
| Net Assets | 39.4 M | 6.38 M | 37.9 B | 83.75% |
| Number of Holdings | 63 | 24 | 416 | 68.13% |
| Net Assets in Top 10 | 18.4 M | 3.49 M | 22.8 B | 81.88% |
| Weighting of Top 10 | 46.76% | 16.2% | 79.4% | 45.00% |
Top 10 Holdings
- FIRST AM-TR OB-X 7.72%
- GILEAD SCIENCES 7.18%
- ASTRAZENECA PLC 5.63%
- VERTEX PHARM 5.60%
- IONIS PHARMACEUT 3.74%
- INSMED INC 3.57%
- INCYTE CORP 3.41%
- ROIVANT SCIENCES 3.36%
- ARGENX SE - ADR 3.33%
- NEUROCRINE BIOSC 3.22%
Asset Allocation
| Weighting | Return Low | Return High | LYFCX % Rank | |
|---|---|---|---|---|
| Stocks | 92.43% | 88.27% | 106.13% | 90.00% |
| Cash | 7.72% | 0.00% | 32.31% | 7.50% |
| Preferred Stocks | 0.00% | 0.00% | 7.86% | 50.00% |
| Other | 0.00% | -22.99% | 4.13% | 48.75% |
| Convertible Bonds | 0.00% | 0.00% | 0.37% | 30.97% |
| Bonds | 0.00% | 0.00% | 12.39% | 39.38% |
Stock Sector Breakdown
| Weighting | Return Low | Return High | LYFCX % Rank | |
|---|---|---|---|---|
| Healthcare | 100.00% | 59.26% | 100.00% | 10.97% |
| Utilities | 0.00% | 0.00% | 0.00% | 25.81% |
| Technology | 0.00% | 0.00% | 22.69% | 30.97% |
| Real Estate | 0.00% | 0.00% | 5.89% | 30.97% |
| Industrials | 0.00% | 0.00% | 7.02% | 30.97% |
| Financial Services | 0.00% | 0.00% | 1.60% | 46.45% |
| Energy | 0.00% | 0.00% | 0.00% | 25.81% |
| Communication Services | 0.00% | 0.00% | 9.11% | 29.03% |
| Consumer Defense | 0.00% | 0.00% | 25.73% | 33.55% |
| Consumer Cyclical | 0.00% | 0.00% | 1.92% | 30.97% |
| Basic Materials | 0.00% | 0.00% | 7.16% | 49.03% |
Stock Geographic Breakdown
| Weighting | Return Low | Return High | LYFCX % Rank | |
|---|---|---|---|---|
| US | 92.43% | 60.50% | 104.41% | 61.25% |
| Non US | 0.00% | 0.00% | 36.86% | 76.25% |
LYFCX - Expenses
Operational Fees
| LYFCX Fees (% of AUM) | Category Return Low | Category Return High | Rank in Category (%) | |
|---|---|---|---|---|
| Expense Ratio | 2.88% | 0.08% | 4.69% | 8.75% |
| Management Fee | 1.25% | 0.03% | 1.25% | 98.75% |
| 12b-1 Fee | 1.00% | 0.00% | 1.00% | 82.67% |
| Administrative Fee | N/A | 0.03% | 0.25% | N/A |
Sales Fees
| LYFCX Fees (% of AUM) | Category Return Low | Category Return High | Rank in Category (%) | |
|---|---|---|---|---|
| Front Load | N/A | 3.50% | 5.75% | N/A |
| Deferred Load | N/A | 1.00% | 1.00% | N/A |
Trading Fees
| LYFCX Fees (% of AUM) | Category Return Low | Category Return High | Rank in Category (%) | |
|---|---|---|---|---|
| Max Redemption Fee | N/A | 1.00% | 1.00% | N/A |
Related Fees
Turnover provides investors a proxy for the trading fees incurred by mutual fund managers who frequently adjust position allocations. Higher turnover means higher trading fees.
| LYFCX Fees (% of AUM) | Category Return Low | Category Return High | Rank in Category (%) | |
|---|---|---|---|---|
| Turnover | N/A | 1.00% | 238.00% | 96.91% |
LYFCX - Distributions
Dividend Yield Analysis
| LYFCX | Category Low | Category High | LYFCX % Rank | |
|---|---|---|---|---|
| Dividend Yield | 0.71% | 0.00% | 6.24% | 11.88% |
Dividend Distribution Analysis
| LYFCX | Category Low | Category High | Category Mod | |
|---|---|---|---|---|
| Dividend Distribution Frequency | Annual | Annual | Annual | Annual |
Net Income Ratio Analysis
| LYFCX | Category Low | Category High | LYFCX % Rank | |
|---|---|---|---|---|
| Net Income Ratio | -2.21% | -2.54% | 1.85% | 98.69% |
Capital Gain Distribution Analysis
| LYFCX | Category Low | Category High | Capital Mode | |
|---|---|---|---|---|
| Capital Gain Distribution Frequency | Annually | Semi-Annually | Annually |
Distributions History
| Date | Amount | Type |
|---|---|---|
| Dec 16, 2025 | $0.115 | OrdinaryDividend |
| Dec 30, 2024 | $0.013 | OrdinaryDividend |
| Dec 13, 2024 | $0.129 | OrdinaryDividend |
| Dec 14, 2023 | $0.340 | OrdinaryDividend |
| Dec 14, 2023 | $0.340 | CapitalGainShortTerm |
| Dec 15, 2022 | $0.549 | CapitalGainLongTerm |
| Dec 16, 2021 | $1.517 | CapitalGainShortTerm |
| Dec 16, 2021 | $0.061 | CapitalGainLongTerm |
| Dec 17, 2020 | $0.351 | OrdinaryDividend |
LYFCX - Fund Manager Analysis
Managers
Mark Charest
Start Date
Tenure
Tenure Rank
Nov 29, 2019
2.5
2.5%
Dr. Charest has served as a portfolio manager of LifeSci Fund Management since 2019. In 2017, he founded Phenomic Capital LLC to provide investment advice and consulting services focused on the healthcare sector. In 2019 Phenomic Capital became an affiliated majority owner of the LifeSci Fund Management. From 2015 to 2016, Mark was SVP at Tekla Capital Management, focused on public and private healthcare technology investments. Between 2012 and 2015, he was Portfolio Manager at New Leaf Venture Partners, focused on public healthcare technology investments. From 2010 to 2012, Dr. Charest was a Kauffman Fellow at Panorama Capital where he served on the board of directors of Itero Biopharmaceuticals and was a board observer at Presidio Pharmaceuticals and PowerVision. Dr. Charest is an inventor on eight drug patents. Prior to his investment career, he held an operating role in the oncology area as a Medicinal Chemistry Lab Manager at the Novartis Institutes for BioMedical Research. Dr. Charest earned his PhD in chemistry and chemical biology from Harvard University as a National Science Foundation Graduate Research Fellow, his MS in chemistry and chemical biology from Harvard University, and his BA in chemistry, with Highest Honors, from Rutgers University.
Tenure Analysis
| Category Low | Category High | Category Average | Category Mode |
|---|---|---|---|
| 0.02 | 24.72 | 8.08 | 0.25 |